Researchers identified unique molecular signatures of blood-brain barrier dysfunction in Alzheimer’s disease. They discovered altered communication between brain vascular cells mediated by VEGFA and SMAD3 molecules. These findings could lead to new diagnostic biomarkers and treatment options for Alzheimer’s.
Researchers developed a novel peptide, KS-133, to target cognitive dysfunction in schizophrenia. By using a brain-targeting peptide, KS-487, they successfully transported KS-133 across the blood-brain barrier. Their nanoparticle-based drug delivery system improved cognitive functions in mice, offering a new therapeutic strategy.
A new study shows GLP-1 receptor agonists increase pre-meal fullness by activating neurons in the dorsomedial hypothalamus. This mechanism helps prevent overeating, offering insights into obesity treatment. The research highlights how GLP-1 impacts food perception and hypothalamic responses to food cues, enhancing satiation before food intake.
New research shows people are more likely to accuse others of lying when AI makes the accusation first. This insight highlights the potential social impact of AI in lie detection and suggests caution for policymakers. The study found AI’s presence increased accusation rates and influenced behavior, despite people’s general reluctance to use AI lie detection […]
A new study documents the first case of Down syndrome in a Neandertal child named “Tina,” found in Spain. Despite severe hearing loss and vertigo, Tina survived to at least 6 years old, indicating she received extensive care from her group. This discovery highlights the Neandertals’ capacity for altruistic behavior.
